View Single Post
Old 04-02-2010, 07:42 PM   #11
Senior Member
Location: Rochester, MN

Join Date: Mar 2009
Posts: 191

The point with RPKM that I do not like, it is that I do not feel that it can handle different coverages.
I totally agree with you Chema. RPKM is biased for testing differential expression for longer genes. See the following paper:

HTML Code:
and also other papers by Oshlack and Wakefield.
RockChalkJayhawk is offline   Reply With Quote