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  • Hello everyone

    Hi,

    I am a third year Computer Science PhD student from US working on RNASeq. I spent good amount of time doing literature review and using the major softwares to go through the RNASeq workflow.

    Now, I am looking for some interesting computational problems- which can be transformed into a big project. I looked into single-cell RNA sequencing, Time course RNA Seq also. But, I am looking for some problems which are biologically interesting (computationally extensive though) but not yet done by any software yet.
    Or what are some big problems which are not considered well in different softwares?

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  • seqadmin
    Essential Discoveries and Tools in Epitranscriptomics
    by seqadmin


    The field of epigenetics has traditionally concentrated more on DNA and how changes like methylation and phosphorylation of histones impact gene expression and regulation. However, our increased understanding of RNA modifications and their importance in cellular processes has led to a rise in epitranscriptomics research. “Epitranscriptomics brings together the concepts of epigenetics and gene expression,” explained Adrien Leger, PhD, Principal Research Scientist on Modified Bases...
    Yesterday, 07:01 AM
  • seqadmin
    Current Approaches to Protein Sequencing
    by seqadmin


    Proteins are often described as the workhorses of the cell, and identifying their sequences is key to understanding their role in biological processes and disease. Currently, the most common technique used to determine protein sequences is mass spectrometry. While still a valuable tool, mass spectrometry faces several limitations and requires a highly experienced scientist familiar with the equipment to operate it. Additionally, other proteomic methods, like affinity assays, are constrained...
    04-04-2024, 04:25 PM

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