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  • Script to count parsimony informative sites

    I have hundreds of alignments, and I am curious if there is a script or tool out there that can simply count the number of parsimony informative sites in any given alignment?

    I know you can get this information by loading it into a phylogenetics program (e.g. PAUP or MrBayes), but if anyone knows of a script that can do this so it can be automated and done quickly I'd appreciate it!

  • #2
    No promises that it works correctly, but here's something that I had sitting around:

    count and extract parsimony informative SNPs from a multi-fasta - extract_PI_SNPs.py


    You need BioPython to run and it assumes no gaps. In addition to reporting the number of PI SNPs, it also prints a new multi-fasta with only those sites included. Feel free to edit it as you see fit.

    J

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    • #3
      Thanks

      Thanks for that script!

      I also found out you can do it with the function pis() in the R library phyloch. That function also allows for gaps.

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