View Single Post
Old 04-26-2012, 01:56 PM   #1
Junior Member
Location: USA

Join Date: Dec 2011
Posts: 5
Default Copy number variation..on chromosome level...or ploidy with sequencing

I was wondering if we can use low coverage sequencing to detect the copy number variation. I am not interested in gene level or micro level but rather a whole chromosome duplication, deletion or even the whole ploidy change. I know flow cytometry is cheaper option to determine ploidy but wondering if it is achievable with multiplexing in a single lane of Illumina Hiseq. And oh, I do not have reference sequences.

Thank you
antu82 is offline   Reply With Quote