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Old 05-15-2013, 10:51 AM   #1
ajthomas
Senior Member
 
Location: Utah

Join Date: Mar 2010
Posts: 166
Default your experience with the Proton

We are considering buying either a Proton or a MiSeq. A little background: we're a small core facility at a university and we have a 454 only. We're running a lot of amplicons on the 454, but every other application has moved to other instruments. The advantage I see of the Proton is lower per-base cost and the ability to do transcriptomes (especially with the PII chip when that is available) and other larger projects. The advantage of the MiSeq is ease of use and longer reads (better for the amplicons we're currently doing, some of which are moving to the MiSeq in the near future).

So, I would like to know from you what has been your experience with the Proton? How reliable is it and how easy is it to run? Does yours get a lot of use and what kind of projects is it being used for? How does real-world performance compare to the published specs? Are you glad you bought it? Any other thoughts?
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