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Old 04-29-2011, 12:37 AM   #9
jflores
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Location: Mexico

Join Date: Mar 2011
Posts: 7
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Quote:
Originally Posted by roman.sergio View Post
Hello

Did you already found how to detect the CNV with your data from non control case study?

I am continuing seraching for a solution.

Regards,

Sergio
Hi Sergio,

With CNV-seq in mind and for non-control-case studies you can basically choose whatever reference you want. There might be some issues to worry about like what population the reference you choose come from? or what's the coverage .. It will depend on your purpose and the features of your sample to analyze.
Iíve seen some studies taking the health individual NA10851 from the 1000 genomes data as a control/reference.

ftp://ftp.1000genomes.ebi.ac.uk/vol1/ftp/

Hope can help,
Jose Flores
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J. Rodrigo Flores
jflores@lcg.unam.mx
Center for Genomic Sciences, UNAM, Mexico
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