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Old 07-02-2019, 04:01 AM   #2
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Location: East Coast USA

Join Date: Feb 2008
Posts: 6,990

If you only plan to do one or two runs a month it may not be worth your time. Sequencers have fine capillaries, complex electronics and are generally happier when run reasonably continuously. The machine will run for a time but you are going to inevitably need service on it at some point and then things will get rather expensive fast, without a service contract.

Illumina is actively trying to wean people off older HiSeq. Even though reagents are supposed to remain available for another 2-4 years, their price has been going up steadily. So the rapid runs you find attractive now will likely cost more every passing year.

That said, since the price is right (free) and if you are willing to gamble away some of your time/effort, you will be able to get some sequencing out of the machine.
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