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Old 02-21-2012, 10:16 AM   #27
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Location: Germany

Join Date: Feb 2012
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Originally Posted by Nanoporous View Post
Their nanopore array is possibly the most innovative feature of their system - they have developed some sort of a synthetic polymer that replaces the lipid bilayer. So they are able to embed the protein in the polymer and array them on the chip overcoming the Poisson distribution.

If he specifically mentioned overcoming Poisson, did he say how successful that was? I would say you can tweak it some, but that you'll always have a bit of the old alea iacta stuff going on, with some no-shows and some doubles. It might make sense to ship dry and have some priming program run after activation. You clearly have to be recording in order to array the pores so you can follow them go in and it would take some time, I guess, until you have a sizeable portion of membranes with exactly a single pore. Fascinating stuff.
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