Dear all,
I try to get an idea of the base coverage required for the different sequencing applications.
I didn t find any review on this subject so if you know a nice paper or can complete the followings, your are more than welcome:
- whole genome resequencing: 40x genome size (Nature 464, 587-591)
- SNPs call: 31x genome size (Genome Res. 2010. 20: 273-280)
- de novo genome modelling: 100x ??
- de novo transcriptome modelling: 100x??
- transcript expression studies: ??
Oliviera
I try to get an idea of the base coverage required for the different sequencing applications.
I didn t find any review on this subject so if you know a nice paper or can complete the followings, your are more than welcome:
- whole genome resequencing: 40x genome size (Nature 464, 587-591)
- SNPs call: 31x genome size (Genome Res. 2010. 20: 273-280)
- de novo genome modelling: 100x ??
- de novo transcriptome modelling: 100x??
- transcript expression studies: ??
Oliviera
Comment