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Old 10-23-2013, 03:53 PM   #2
lethalfang
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Location: San Francisco, CA

Join Date: Aug 2011
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Quote:
Originally Posted by zhaopeihua View Post
hi:
What are "variant allele fraction" when talking about somatic mutations?
The fraction of alleles in the sample that are mutations.
For instance, if all cells contains the same heterogeneous mutation (e.g., 100% tumor cell purity if you're looking at tumor cells), the variant allele fraction would be 50% (half-half from each chromosome).
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