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Old 01-24-2017, 12:57 AM   #12
Location: Sweden

Join Date: Jan 2017
Posts: 18

Originally Posted by Brian Bushnell View Post
In some situations, like RNA-seq, single-cell, or metagenomes, in which the sequences have an exponential coverage distribution, you will NEVER reach zero.
But could this approach still be used with e.g. metagenomics data to get some kind of feeling for if the sequencing depth is deep enough? I guess what I'm really asking is whether you think it would be reasonable to still expect it decrease (even if it doesn't reach zero, but instead bottoms out somewhere higher)?
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