I've run several RNA samples on the Bioanalyzer (eukaryotic pico kit) and the ribosomal peaks look decent. There is though a peculiar, smaller peak just before the main 18S peak. Does this indicate degradation - it seems strange that all samples should have such and identical peak - or could it be to do with the kit/reagents? Thanks.
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NGS has revolutionized clinical microbiology by offering new ways to identify and surveil pathogens without prior knowledge of the target. One popular approach is 16S rRNA and ITS amplicon sequencing, which targets specific microbial markers. But studies are increasingly incorporating shotgun metagenomics, a technique that sequences all DNA from a sample without targeting specific microbial markers. This approach allows more detailed taxonomic classification, detection...10-30-2026, 06:46 AM -
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