Your own genome

[kmewis]

Just a little thread to toss around some ideas!

If you could sequence your own whole genome and analyze it, what would be on the list of things you'd want to search for? Where (databases) would you compare it to look for SNPs of significance, or rearrangements that might give you some sort of information?

With all these companies now offering full genome sequencing and counseling, it makes me wonder what they'd be offering that a person with access to a sequencer and basic bioinformatic knowledge wouldn't be able to do on their own time.

$350k for my own genome is a lot more expensive than a bottle of whiskey and some DNA passed off to a sequencing tech is what I'm saying!

[lry198010]

If you could sequence your own whole genome and analyze it, what would be on the list of things you'd want to search for? Where (databases) would you compare it to look for SNPs of significance, or rearrangements that might give you some sort of information?

If I could do, I will search for the loci that contributed to the risk of asthma and relative disease. But, I didn't know how to get reference! Maybe I will sequence all the member of our family to trace the loci of asthma!

[Jeremy]

With all these companies now offering full genome sequencing and counseling, it makes me wonder what they'd be offering that a person with access to a sequencer and basic bioinformatic knowledge wouldn't be able to do on their own time.

You could probably get more information if you did it yourself. The reports that they give only include risk alleles for a hand-full of diseases from what I have seen, depends on the vendor I guess tho.