Unconfigured Ad

Collapse
X
 
  • Time
  • Show
Clear All
new posts
  • bonnofthejungle
    Junior Member
    • Jul 2019
    • 1

    #1

    Establishing a metagenomics lab/hardware requirements

    Hello all!

    I recently joined a lab that would like to set up a bioinformatics side of things. We do a lot of stool sample shotgun sequencing and we get loads of samples (in the thousands) sequenced to medium - deep sequencing (~10million reads per sample). At the moment we are still at the sequencing stage, so no analysis has started yet of the sequencing results.

    For that we need to greatly upgrade our hardware. If one were to buy a workstation (instead of regular desktop or perhaps a server) what kind of specs would you suggest this workstation to have?

    I am thinking the three things that are super important in decreasing order is RAM, space, and processing power.

    For RAM, would you say for the amount of samples i referred to above, would below 100Gb be sufficient or should we be aiming for more?

    For space, would you say tens of terabytes would be sufficient or should we aim already for hundreds of terabytes.

    Finally, what kind of CPUs would you recommend? Would the intel ones be good enough i7 or i9? Is something else more state of the art this kind of analysis?

    I have tried to do as much research as i can on my own but i am no bioinformatician! Any input would help

Latest Articles

Collapse

  • SEQadmin2
    Beyond CRISPR/Cas9: Understand, Choose, and Use the Right Genome Editing Tool
    by SEQadmin2



    CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).

    Despite this, “CRISPR helped turn genome editing from a specialized technique into
    ...
    07-31-2026, 11:01 AM
  • SEQadmin2
    Proteomic Platforms: How to Choose the Right Analytical Strategy to Improve Detection and Clinical Applications
    by SEQadmin2


    Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.

    The systematic characterization of the human proteome has
    ...
    07-20-2026, 11:48 AM
  • SEQadmin2
    Advanced Sequencing Platforms Tackle Neuroscience’s Toughest Genomics Problems
    by SEQadmin2



    Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
    ...
    07-09-2026, 11:10 AM

ad_right_rmr

Collapse

News

Collapse

Topics Statistics Last Post
Started by SEQadmin2, Today, 07:41 AM
0 responses
9 views
0 reactions
Last Post SEQadmin2  
Started by SEQadmin2, 08-03-2026, 10:13 AM
0 responses
25 views
0 reactions
Last Post SEQadmin2  
Started by SEQadmin2, 07-31-2026, 02:55 AM
0 responses
38 views
0 reactions
Last Post SEQadmin2  
Started by SEQadmin2, 07-24-2026, 12:17 PM
0 responses
25 views
0 reactions
Last Post SEQadmin2  
Working...