small RNA cloning kit: Illumina vs NEB

[wingless]

Hi,

I have been cloning small RNAs with the Illumina TruSeq kit so far.
However, it is pretty expensive, and I realized that there is also a NEB kit for that purpose which is half the price ($1200 vs $2400).

Has anyone by any chance compared how the two kits perform, i.e. whether they generate similar results? There are some mentions of "normal" RNA cloning kits comparisons, but I couldn't find anything about the small ones.

Thanks!

[nucacidhunter]

Comparison of three major kits has been reported: http://www.biomedcentral.com/1471-2164/14/319

This new chemistry http://www.trilinkbiotech.com/work/sRNAPrep.pdf sounds good as dimer prevention technology is innovative and completely different from major kits approach. I do not know if a complete library prep kit has been released using this technology yet.

[wingless]

Yeah, thanks. I came across this comparison too, but their small RNA input is really tiny (2 ng, while the recommended is 10+ ng), and I was hoping that perhaps if anyone has done the comparison starting more RNA and got smaller variation?...