Unconfigured Ad

Collapse
X
 
  • Time
  • Show
Clear All
new posts
  • bio_informatics
    Senior Member
    • Nov 2013
    • 182

    #1

    Download fasta file for pdb id from uniprot

    Hi Members,
    I've a list of pdb id [some ~80].
    I want to download their fasta file from Uniprot.

    I have been unable to find URL which can be then utilized using wget or curl.

    example: 2rh1
    Please help.
    Bioinformaticscally calm
  • GenoMax
    Senior Member
    • Feb 2008
    • 7142

    #2
    If you have 80 perhaps getting the fasta files for UniProt/SwissProt and UniProt/TreEmbl (ftp://ftp.uniprot.org/pub/databases/...base/complete/) then parsing out the sequences you need.

    Comment

    • bio_informatics
      Senior Member
      • Nov 2013
      • 182

      #3
      Thank you GenoM for your reply.

      I downloaded sprot [swissprot] file. On going through it, I found protein name as:

      >sp|Q6GZX3|002L_FRG3G Uncharacterized protein 002L OS=Frog virus 3 (isolate Goorha) GN=FV3-002L PE=4 SV=1

      I have pdb ids with me, and not much information other than that.
      I was wondering how would I be able to get hold my data from this header.

      Appreciate your inputs.

      Originally posted by GenoMax View Post
      If you have 80 perhaps getting the fasta files for UniProt/SwissProt and UniProt/TreEmbl (ftp://ftp.uniprot.org/pub/databases/...base/complete/) then parsing out the sequences you need.
      Bioinformaticscally calm

      Comment

      • bio_informatics
        Senior Member
        • Nov 2013
        • 182

        #4
        I guess 6GZX are the PDB ids. I am randomly grep-ping the ids and have hit few of them.
        But there are multiple entries for one such id.
        Code:
        $ grep -i "2m3g" uniprot_sprot.fasta
        >sp|Q2M3G0|ABCB5_HUMAN ATP-binding cassette sub-family B member 5 OS=Homo sapiens GN=ABCB5 PE=1 SV=3

        >sp|Q2M3G4|SHRM1_HUMAN Protein Shroom1 OS=Homo sapiens GN=SHROOM1 PE=1 SV=1
        Bioinformaticscally calm

        Comment

        • GenoMax
          Senior Member
          • Feb 2008
          • 7142

          #5
          PDB to Uniprot ID's: http://www.uniprot.org/docs/pdbtosp

          Comment

          • bio_informatics
            Senior Member
            • Nov 2013
            • 182

            #6
            Wow. That helps a lot. Thank you.

            FASTA sequence/file can be downloaded using wget from a URL:
            Ex:
            pdb id -2E9Q
            Code:
            wget "http://www.uniprot.org/uniprot/?query=database%3A%28type%3Apdb+2E9Q%29&format=fasta"
            Note: There can be multiple sequences of one PDB id.

            Last edited by bio_informatics; 09-12-2014, 06:45 AM.
            Bioinformaticscally calm

            Comment

            Latest Articles

            Collapse

            • SEQadmin2
              Beyond CRISPR/Cas9: Understand, Choose, and Use the Right Genome Editing Tool
              by SEQadmin2



              CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).

              Despite this, “CRISPR helped turn genome editing from a specialized technique into
              ...
              07-31-2026, 11:01 AM
            • SEQadmin2
              Proteomic Platforms: How to Choose the Right Analytical Strategy to Improve Detection and Clinical Applications
              by SEQadmin2


              Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.

              The systematic characterization of the human proteome has
              ...
              07-20-2026, 11:48 AM

            ad_right_rmr

            Collapse

            News

            Collapse

            Topics Statistics Last Post
            Started by SEQadmin2, Yesterday, 10:35 AM
            0 responses
            7 views
            0 reactions
            Last Post SEQadmin2  
            Started by SEQadmin2, 08-06-2026, 07:41 AM
            0 responses
            25 views
            0 reactions
            Last Post SEQadmin2  
            Started by SEQadmin2, 08-03-2026, 10:13 AM
            0 responses
            45 views
            0 reactions
            Last Post SEQadmin2  
            Started by SEQadmin2, 07-31-2026, 02:55 AM
            0 responses
            48 views
            0 reactions
            Last Post SEQadmin2  
            Working...