Unconfigured Ad

Collapse
X
 
  • Filter
  • Time
  • Show
Clear All
new posts
  • genelab
    Member
    • Nov 2009
    • 27

    How to quick index the sam record according to the read name?

    How to quick index the sam record according to the read name?

    assum i hava a read which named "afaNma_1", and this read has record in the sam format file;

    I want to index and get the samRecord of read "afaNma_1" in this sam file quickly, Can anyone tell me how should i do?


    Thanks
  • Bio.X2Y
    Member
    • Apr 2010
    • 46

    #2
    I'm not aware of anything convenient for doing this, but someone else might be able to shed light.

    If you are comfortable with programming, I'd sort the file by name, leaving the header records on top (samtools probably has something for this). Then write a program to pluck out your target record using a binary search algorithm (http://en.wikipedia.org/wiki/Binary_search_algorithm). Java has a RandomAccessFile class for quickly accessing arbitary file bytes, though I'm sure other languages have their equivalents. The tricky part will be finding the start of a record containing an arbitary byte - you will have to work backwards to find a newline or the start-of-file.

    I know this isn't creating an index, but it should be lightning fast for practical purposes.

    Comment

    • brentp
      Member
      • Apr 2010
      • 72

      #3
      you can use this
      miscellaneous scripts for bioinformatics/genomics that dont merit their own repo. - brentp/bio-playground

      if you have python and tokyo-cabinet

      Comment

      • maubp
        Peter (Biopython etc)
        • Jul 2009
        • 1544

        #4
        I have some still experimental code for SAM/BAM with indexing by name for Biopython here: http://github.com/peterjc/biopython/...-sam-bam-index

        Comment

        Latest Articles

        Collapse

        • SEQadmin2
          Proteomic Platforms: How to Choose the Right Analytical Strategy to Improve Detection and Clinical Applications
          by SEQadmin2


          Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.

          The systematic characterization of the human proteome has
          ...
          07-20-2026, 11:48 AM
        • SEQadmin2
          Advanced Sequencing Platforms Tackle Neuroscience’s Toughest Genomics Problems
          by SEQadmin2



          Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
          ...
          07-09-2026, 11:10 AM
        • SEQadmin2
          Cancer Drug Resistance: The Lingering Barrier to Rising Survival
          by SEQadmin2



          Cancer survival rates have significantly increased in the last few decades in the United States, reaching a combined 70% 5-year survival rate by 2021. Behind this number, there are years of research to find new therapies, drug targets, and early detection methods. But there is one core challenge that keeps slowing down these advances, and it’s about drug resistance.

          There is no single reason why many patients don’t respond to treatment as expected. Cancer is...
          07-08-2026, 05:17 AM

        ad_right_rmr

        Collapse

        News

        Collapse

        Topics Statistics Last Post
        Started by SEQadmin2, Today, 11:41 AM
        0 responses
        9 views
        0 reactions
        Last Post SEQadmin2  
        Started by SEQadmin2, 07-20-2026, 11:10 AM
        0 responses
        23 views
        0 reactions
        Last Post SEQadmin2  
        Started by SEQadmin2, 07-13-2026, 10:26 AM
        0 responses
        35 views
        0 reactions
        Last Post SEQadmin2  
        Started by SEQadmin2, 07-09-2026, 10:04 AM
        0 responses
        45 views
        0 reactions
        Last Post SEQadmin2  
        Working...