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To apply: http://www.chop.edu.apply2jobs.com Req # 10-21682
The Center for Biomedical Informatics is rapidly expanding its next generation sequencing capabilities in the areas of data processing, analysis, and interpretation to support CHOP’s large investment in genomics-based personalized medicine. The Senior Next Generation Sequencing Analyst will be responsible for development of a robust data processing and analysis engine in conjunction with an enterprise-level next generation sequencing (NGS) facility. This position will build an informatics framework for NGS data management, processing, and analysis by interacting directly with clinical and bench researchers who are involved in genome-wide studies, biomarker discovery and validation, clinical diagnostics, and other biomedical research. He or she will ensure that data flows and analysis modules are robust and result in actionable data with interpretable results in a multidisciplinary team-based setting. The Senior Next Generation Sequencing Analyst will assess the data pipeline and analysis needs of the institution and will implement optimal solutions from available open and commercial sources or will develop customized modules. This position demands an individual with superior technical programming skills in one or more computer languages who can quickly apply this knowledge to define a “best path” for complex data types resulting from multiple NGS platforms and applications. In addition to the technical demands of the position, the successful candidate will communicate at a high level with world-class researchers and highly capable informatics staff, will objectively assess the capabilities and limitations of pipeline components, and will ultimately serve as a premiere informatics and development resource in CHOP’s next generation sequencing program. There is a strong preference for candidates with specific knowledge of NGS vernacular and issues such as data quality and platform mechanics and formats.
BS required/MS strongly preferred in informatics, computational biology, or a related discipline.
5 or more years experience in data processing pipeline development and/or programming within a bioinformatics environment required.
Proficiency in UNIX/LINUX environment required.
Proficiency in at least one scripting language such as Perl, Python, or Ruby required.
High Performance Computing skills required.
Proficiency in Java and/or C/C++ strongly preferred
Previous experience in data modeling and applications of next generation sequencing data is strongly preferred.
Familiarity with bioinformatics resources and software preferred.
Proficiency in SQL and HTML preferred.
Experience with statistical genetics preferred.
Excellent oral and written communication skills required.
The Center for Biomedical Informatics is rapidly expanding its next generation sequencing capabilities in the areas of data processing, analysis, and interpretation to support CHOP’s large investment in genomics-based personalized medicine. The Senior Next Generation Sequencing Analyst will be responsible for development of a robust data processing and analysis engine in conjunction with an enterprise-level next generation sequencing (NGS) facility. This position will build an informatics framework for NGS data management, processing, and analysis by interacting directly with clinical and bench researchers who are involved in genome-wide studies, biomarker discovery and validation, clinical diagnostics, and other biomedical research. He or she will ensure that data flows and analysis modules are robust and result in actionable data with interpretable results in a multidisciplinary team-based setting. The Senior Next Generation Sequencing Analyst will assess the data pipeline and analysis needs of the institution and will implement optimal solutions from available open and commercial sources or will develop customized modules. This position demands an individual with superior technical programming skills in one or more computer languages who can quickly apply this knowledge to define a “best path” for complex data types resulting from multiple NGS platforms and applications. In addition to the technical demands of the position, the successful candidate will communicate at a high level with world-class researchers and highly capable informatics staff, will objectively assess the capabilities and limitations of pipeline components, and will ultimately serve as a premiere informatics and development resource in CHOP’s next generation sequencing program. There is a strong preference for candidates with specific knowledge of NGS vernacular and issues such as data quality and platform mechanics and formats.
BS required/MS strongly preferred in informatics, computational biology, or a related discipline.
5 or more years experience in data processing pipeline development and/or programming within a bioinformatics environment required.
Proficiency in UNIX/LINUX environment required.
Proficiency in at least one scripting language such as Perl, Python, or Ruby required.
High Performance Computing skills required.
Proficiency in Java and/or C/C++ strongly preferred
Previous experience in data modeling and applications of next generation sequencing data is strongly preferred.
Familiarity with bioinformatics resources and software preferred.
Proficiency in SQL and HTML preferred.
Experience with statistical genetics preferred.
Excellent oral and written communication skills required.