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DNA Electronics partners with Roche to develop semiconductor based sequencing system
DNA Electronics, a fabless semiconductor provider of solutions for real-time DNA and RNA analysis, announced today that it has entered a partnership with 454 Life Sciences, a Roche Company. The collaboration will focus on the development of a low-cost, high-throughput, long read, high density DNA sequencing system. As part of the agreement, DNA Electronics has signed a non-exclusive licence to provide relevant IP from its proprietary semiconductor technology portfolio to Roche. This technology which enables sensitive detection of nucleotide incorporation during sequencing will build on 454 Life Sciences’ current pyrosequencing-based platform. The collaboration leverages DNA Electronics’ unique knowledge of semiconductor design and expertise in pH-mediated detection of nucleotide insertions with 454 Life Sciences’ long read sequencing chemistry to produce a seamless evolution from optical detection to low-cost, highly scalable electrochemical detection.
pdf of press release: http://www.dnae.co.uk/images/2010-11...%20License.pdf -
And it will be called "Ion Current"?...Comment
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This was pretty interesting to me also...especially since DNA Electronics licensed their tech to Ion Torrent as well.
Maybe we're heading for a big IP battle! Exciting...Comment
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Exciting indeed eco
I think the next 2 years is going to be great viewing for the impartial observer - and this site will probably give a pretty good front row seat!Comment
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Sample prep for ISFETs
I wonder if emPCR IP for sample prep will also fall into the fray. All the ISFET sensor tech will need a bead in a well for measurement until solid state nanopores come along.Comment
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CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...07-31-2026, 11:01 AM -
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has...07-20-2026, 11:48 AM -
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
...07-09-2026, 11:10 AM
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