In IGV, is it possible to display the six-frame (amino-acid) translation of the reference genome?
That would be helpful for assessing the accuracy of gene models.
That would be helpful for assessing the accuracy of gene models.
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I don't know, but you can do it in Tablet. -
I contacted igv-help [at] broadinstitute.org . I got a reply saying that the six-frame translation will be available in the upcoming IGV 2.0 release, which you can access at http://www.broadinstitute.org/software/igv/wiki .Comment
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CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...07-31-2026, 11:01 AM
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