SEQanswers

Go Back   SEQanswers > Bioinformatics > Bioinformatics



Similar Threads
Thread Thread Starter Forum Replies Last Post
tool to determine sequence divergence based on snp density? odoyle81 Bioinformatics 0 03-28-2012 11:46 AM
Exome sequence annotation ketan_bnf Bioinformatics 1 01-06-2011 12:21 PM
How to determine 454 paired end adaptor sequence edge 454 Pyrosequencing 10 10-01-2009 12:23 AM

Reply
 
Thread Tools
Old 11-18-2013, 02:32 PM   #1
rbagnall
Member
 
Location: Sydney, Australia

Join Date: Jun 2010
Posts: 34
Default Determine ethnicity from exome sequence

I have data from 40 exomes and they are from de-identified post-mortem samples.

There are many SNPs that have a higher frequency in Asian populations compared to Europeans, for example. When I compare my data to available SNP frequencies I would like to match the ethnicity. Have the collective observed alleles at such sites been used to determine the ethnicity from exome data?

Also, I have been able to reconstruct the Mitochondrial DNA sequence from off-target reads, using MitoSeek. I can determine the mitochondrial haplotype using Mitotool website, and since particular mitochondrial haplogroups can be enriched in ethnic groups, can this extra information support ethnicity?

Any thoughts or comments welcome.
rbagnall is offline   Reply With Quote
Old 11-18-2013, 04:59 PM   #2
GenoMax
Senior Member
 
Location: East Coast USA

Join Date: Feb 2008
Posts: 6,747
Default

http://genomemedicine.com/content/5/7/69
GenoMax is offline   Reply With Quote
Reply

Tags
ethnicity, exome analysis

Thread Tools

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off




All times are GMT -8. The time now is 01:18 AM.


Powered by vBulletin® Version 3.8.9
Copyright ©2000 - 2018, vBulletin Solutions, Inc.
Single Sign On provided by vBSSO