Hi,
I am looking to filter out the variants that lie on a segmental duplication and the ones that are not in a conserved region. I have used Annovar to annotate the variants and it provides a score for the conservation and a value for the segmental duplication. I do not understand these values, can someone explain what they mean? What cutoff should I be using for my purposes?
thanks
I am looking to filter out the variants that lie on a segmental duplication and the ones that are not in a conserved region. I have used Annovar to annotate the variants and it provides a score for the conservation and a value for the segmental duplication. I do not understand these values, can someone explain what they mean? What cutoff should I be using for my purposes?
thanks
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