Tweet
NextSeq is good for small RNA libraries?
Any systematic comparison of both systems?
Any systematic comparison of both systems?
-
-
I guess NextSeq is good for RNA Seq, Exome and ChIP seq also.. -
Both are sequencers by function. Considering their sequence outputs, you can decide which is appropriate for the application you intend to use them for and the number of samples you need to multiplex.
NextSeq uses 2-color chemistry as opposed to HiSeq 4000 (which uses standard Illumina type) so that may be one consideration. HiSeq 4000 requires libraries of more exacting specifications (in terms of insert size etc) that would be one more consideration.Comment
-
The sequencing world is rapidly changing due to declining costs, enhanced accuracies, and the advent of newer, cutting-edge instruments. Equally important to these developments are improvements in sequencing analysis, a process that converts vast amounts of raw data into a comprehensible and meaningful form. This complex task requires expertise and the right analysis tools. In this article, we highlight the progress and innovation in sequencing analysis by reviewing several of the...Yesterday, 07:48 AM -
The field of epigenetics has traditionally concentrated more on DNA and how changes like methylation and phosphorylation of histones impact gene expression and regulation. However, our increased understanding of RNA modifications and their importance in cellular processes has led to a rise in epitranscriptomics research. “Epitranscriptomics brings together the concepts of epigenetics and gene expression,” explained Adrien Leger, PhD, Principal Research Scientist...04-22-2024, 07:01 AM
Comment