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  • Bioinformatician (Cancer Genomics Group) in London, UK

    The Cancer Genomics Group studies the genetic and mutational basis of cancer with a focus on lymphoma and leukaemia.

    You will work with high throughput sequencing data derived from lymphomas and leukaemias. You will create a database integrating somatic mutations, germline variation and RNA expression and build a web interface to simplify access to the data. You will also develop novel approaches for the analysis and visualisation of these datasets. Tools developed would be published as an R package and/or online database.

    You will also spend a small portion of your time working in the laboratory to better understand the process by which biological data is generated.

    Main duties / key responsibilities:
    • Contribution toward the group’s computational infrastructure, algorithms and software
    • Publish data and software tools
    • Participation in training by providing advice and information to members of the group
    • To collaborate with affiliated scientists and other researchers within the MRC, Imperial College and elsewhere as appropriate.


    Location: MRC Clinical Sciences Centre at Imperial College London's Hammersmith Hospital Campus

    Apply at the following website: http://www.topcareer.jobs/Vacancy/irc126453_4018.aspx

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  • seqadmin
    Current Approaches to Protein Sequencing
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    Proteins are often described as the workhorses of the cell, and identifying their sequences is key to understanding their role in biological processes and disease. Currently, the most common technique used to determine protein sequences is mass spectrometry. While still a valuable tool, mass spectrometry faces several limitations and requires a highly experienced scientist familiar with the equipment to operate it. Additionally, other proteomic methods, like affinity assays, are constrained...
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    Despite advancements in sequencing platforms and related sample preparation technologies, certain sample types continue to present significant challenges that can compromise sequencing results. Pedro Echave, Senior Manager of the Global Business Segment at Revvity, explained that the success of a sequencing experiment ultimately depends on the amount and integrity of the nucleic acid template (RNA or DNA) obtained from a sample. “The better the quality of the nucleic acid isolated...
    03-22-2024, 06:39 AM

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