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I have merged VCF files of every individuals of a particular population using VCF merge. But I am not sure which SNP is coming from which individual. I tried to convert the merged VCF file in PGDSpider to generate GENEPOP format data to use in Lositan for Outlier detection. However, Lositan only detects one population. What could be the best way to merge different VCF files for different populations into one Genepop file to use in Lositan for Outlier detection?
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The field of epigenetics has traditionally concentrated more on DNA and how changes like methylation and phosphorylation of histones impact gene expression and regulation. However, our increased understanding of RNA modifications and their importance in cellular processes has led to a rise in epitranscriptomics research. “Epitranscriptomics brings together the concepts of epigenetics and gene expression,” explained Adrien Leger, PhD, Principal Research Scientist on Modified...Yesterday, 07:01 AM -
Proteins are often described as the workhorses of the cell, and identifying their sequences is key to understanding their role in biological processes and disease. Currently, the most common technique used to determine protein sequences is mass spectrometry. While still a valuable tool, mass spectrometry faces several limitations and requires a highly experienced scientist familiar with the equipment to operate it. Additionally, other proteomic methods, like affinity assays, are constrained...04-04-2024, 04:25 PM