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  • Simple question: Who actually discovered 5 methyl C?

    For some reason this information is not readily available. Just want to know who to give the nobel prize to.

  • #2
    As usual, there is not a simple answer.

    Frequently Rollin Hotchkiss is credited, because he was the first to describe "Epi-cytosine" as a distinct, but chemically very similar base to cytosine. (see Fig. 2)

    However he established no link to epigenetics and also did not investigate the exact chemical structure of "Epi-Cytosine". The identification as 5mC was achieved by Waldo Cohn in 1951 .

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