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Old 03-12-2013, 12:34 PM   #1
dsbreak
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Location: east coast

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Default TopHat-Fusion with DNA-Seq reads?

Has anyone tried using TopHat-Fusion to detect chromosome rearrangements using DNA-Seq reads? Looking over the Methods in the 2011 Genome Biology paper, it sounds like the detection algorithm takes as input "initially unmapped reads" (IUMs) which should still be present in DNA-Seq.
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