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Are there any tools available which will look at reference sequence and list out all the possible locations that can be potentially genes? or alternatively is there a tool that can take a sequence as input and predict if it can be a gene?
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I think you are really talking about 'ab initio' gene prediction (see https://en.wikipedia.org/wiki/Gene_prediction) and there are a lot of tools that can do this.
Maybe Maker could be useful to you: http://www.yandell-lab.org/software/maker.html -
kbradnam, Thanks a ton for this real quick reply.. This is exactly what I am looking for. Has anyone run these tools on entire human reference say hg18 or hg19?Originally posted by kbradnam View PostComment
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The field of epigenetics has traditionally concentrated more on DNA and how changes like methylation and phosphorylation of histones impact gene expression and regulation. However, our increased understanding of RNA modifications and their importance in cellular processes has led to a rise in epitranscriptomics research. “Epitranscriptomics brings together the concepts of epigenetics and gene expression,” explained Adrien Leger, PhD, Principal Research Scientist...04-22-2024, 07:01 AM -
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