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  • paired-end reads and shotgun

    hi,

    I hope someone can help me,
    I just started to study the genomics and learn about the genome sequencing.
    What exactly is the advantage of "paired-end reads"?
    Is the shotgun method basically is producing several libraries containing different size inserts and then followed by single end reads?
    I feel a bit confused with these methods.
    Thank you very much.

    ~merien

  • #2
    Hey Merian,

    Please check out this thread: http://seqanswers.com/forums/showthr...ight=mate+pair

    ...where your question has been answered a bit. If you have more questions, please respond in that thread! Thanks!

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