Have people done detailed comparisons of bacterial communities profiled using amplicon (e.g. 16S) versus shotgun sequencing? I know HMP has done this for certain samples, but I can't seem to find any papers describing their results.
Specifically, I'm looking to see what sort of M^2 values people have seen in Procrustes analysis. For example, Figure 4 of this paper doesn't report M2 values, only p-values which are known to be highly inflated and unreliable...
Specifically, I'm looking to see what sort of M^2 values people have seen in Procrustes analysis. For example, Figure 4 of this paper doesn't report M2 values, only p-values which are known to be highly inflated and unreliable...