Go Back   SEQanswers > Bioinformatics > Bioinformatics

Similar Threads
Thread Thread Starter Forum Replies Last Post
How to Estimate the Average Coverage per RAD Locus fcr De novo discovery 11 02-08-2012 02:58 AM
How can I estimate overall coverage against a reference database? dacotahm Bioinformatics 1 11-22-2011 05:01 PM
Coverage required for SNP detection? Kasycas De novo discovery 3 04-12-2011 11:38 PM
Coverage required to call SNPs from 454 data? prm36 Bioinformatics 0 02-08-2011 09:57 AM
coverage required oliviera General 2 10-18-2010 12:40 AM

Thread Tools
Old 02-16-2012, 02:36 PM   #1
Location: baltimore

Join Date: Oct 2009
Posts: 89
Default How can estimate the required coverage

Hi all:

I do not know how to answer a very simple question. I request you to help me.

How do I know what is the required coverage for a 2 KB region. Someone asked me what is coverage needed to find a very low frequent mutation (10-5 10 to power -5). He wants to find mutation in one locus in a 2KB region. He asked me what is the coverage he should aim for?

To be honest, I do not know how to answer that question. Could someone help me here please.

adrian is offline   Reply With Quote

Thread Tools

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off

All times are GMT -8. The time now is 12:12 PM.

Powered by vBulletin® Version 3.8.9
Copyright ©2000 - 2019, vBulletin Solutions, Inc.
Single Sign On provided by vBSSO