Hey guys,
Simple question. After performing base quality recalibration , if I convert the bam files to sam it's obvious that new quality scores appear where old ones were but the old quality scores are still retained in a later field. Is it possible to delete these older values? I'm not sure if they would affect downstream analysis in any way but if nothing else they make the bam file a lot larger than it needs to be.
Simple question. After performing base quality recalibration , if I convert the bam files to sam it's obvious that new quality scores appear where old ones were but the old quality scores are still retained in a later field. Is it possible to delete these older values? I'm not sure if they would affect downstream analysis in any way but if nothing else they make the bam file a lot larger than it needs to be.
Comment