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  • Annotation of multiple bacterial genomes

    Hi,
    I would like to annotate a subset of the Human Microbiome Project Reference Database http://www.hmpdacc.org/HMREFG/
    and am wondering if anyone has any advice as to the best (and reasonably fast) system to use for annotating multiple bacterial genomes. There are just over 2000 FASTA sequences (~2.3 Gb) - some are complete genomes, and some are scaffolds.

    Thanks!

  • #2
    RAST is an online tool for bacterial genome annotation.
    PROKKA also a great tool.

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