Go Back   SEQanswers > Literature Watch

Similar Threads
Thread Thread Starter Forum Replies Last Post
PubMed: Evaluation of High Throughput Sequencing for identifying known and unknown vi Newsbot! Literature Watch 0 07-01-2011 12:20 PM
PubMed: Evaluation of next-generation sequencing software in mapping and assembly. Newsbot! Literature Watch 0 04-29-2011 12:20 PM
PubMed: Assembly algorithms for next-generation sequencing data. Newsbot! Literature Watch 1 03-10-2010 10:06 AM
Evaluation of next generation sequencing platforms for population targeted sequencing div1982 Literature Watch 0 04-23-2009 07:39 AM
PubMed: Mapping translocation breakpoints by next-generation sequencing. Newsbot! Literature Watch 0 03-11-2008 08:52 AM

Thread Tools
Old 06-17-2011, 03:00 AM   #1
RSS Posting Maniac

Join Date: Feb 2008
Posts: 1,443
Default PubMed: Evaluation of next-generation sequencing software in mapping and assembly.

Syndicated from PubMed RSS Feeds

Evaluation of next-generation sequencing software in mapping and assembly.

J Hum Genet. 2011 Jun 16;

Authors: Bao S, Jiang R, Kwan W, Wang B, Ma X, Song YQ

Next-generation high-throughput DNA sequencing technologies have advanced progressively in sequence-based genomic research and novel biological applications with the promise of sequencing DNA at unprecedented speed. These new non-Sanger-based technologies feature several advantages, when compared with traditional sequencing methods in terms of higher sequencing speed, lower per run cost and higher accuracy. However, reads from next-generation sequencing (NGS) platforms, such as 454/Roche, ABI/SOLiD and Illumina/Solexa, are usually short, thereby restricting the applications of NGS platforms in genome assembly and annotation. We presented an overview of the challenges that these novel technologies meet and particularly illustrated various bioinformatics attempts on mapping and assembly for problem solving. We then compared the performance of several programs in these two fields and further provided advices on selecting suitable tools for specific biological applications.Journal of Human Genetics advance online publication, 16 June 2011; doi:10.1038/jhg.2011.62.

PMID: 21677664 [PubMed - as supplied by publisher]

Newsbot! is offline   Reply With Quote

Thread Tools

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off

All times are GMT -8. The time now is 05:28 AM.

Powered by vBulletin® Version 3.8.9
Copyright ©2000 - 2020, vBulletin Solutions, Inc.
Single Sign On provided by vBSSO