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Old 05-09-2010, 08:00 PM   #1
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Default PubMed: Power of deep sequencing and agilent microarray for gene expression profiling

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Related Articles Power of deep sequencing and agilent microarray for gene expression profiling study.

Mol Biotechnol. 2010 Jun;45(2):101-10

Authors: Feng L, Liu H, Liu Y, Lu Z, Guo G, Guo S, Zheng H, Gao Y, Cheng S, Wang J, Zhang K, Zhang Y


Next-generation sequencing-based Digital Gene Expression tag profiling (DGE) has been used to study the changes in gene expression profiling. To compare the quality of the data generated by microarray and DGE, we examined the gene expression profiles of an in vitro cell model with these platforms. In this study, 17,362 and 15,938 genes were detected by microarray and DGE, respectively, with 13,221 overlapping genes. The correlation coefficients between the technical replicates were >0.99 and the detection variance was
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