Tweet
Science jobs from Flemish Institute for Biotechnology (VIB): job description
Position:
In the Laboratory of Translational Genetics located in Leuven, we are offering a research position in bio-informatics to assist with the analysis of next-generation sequencing data. Ideally, the holder of the position will be scientifically coordinating one or two research projects as a leading scientist and for this, will be able to rely on available data analysis pipelines and IT infrastructure. Additionally, he/she should be willing to participate in a number of collaborative projects within the Laboratory of Translational Genetics by performing advanced bio-informatics consulting and data analysis.
Who should apply for this job?
“If you are fascinated by computer science and have an extra-ordinary curiosity in biology and medicine, if you are driven by a wish to make a difference, if you enjoy and foster team work, if you consider yourself a “bridge” in your social network, if you are not phased by the unknown, willing to push the limits and ready to tackle a challenge, then this job could be just right for you.
Context:
Research in the Laboratory for Translational Genetics aims to unravel the genetic predisposition to cancer and annotate somatic changes in solid tumors with the ultimate aim to discover and functionally validate genetic biomarkers for cancer therapies. To this extend, state-of-the-art high throughput technologies are being used, including large-scale next-generation sequencing of DNA and RNA samples. One of the most exciting ongoing projects concerns the analysis of whole-genome sequencing data of tumor samples. Additionally, a number of projects involve the analysis of ChiPSeq data to characterize epigenetic modifications of (tumor) genomes and based on these data identify novel transcriptional regulatory networks. A key aspect in each of these projects is the use of specialized bio-informatics for primary data analyses (sequence assembly, mapping of deletions, amplifications, tandem duplications, invertions and interchromosomal rearrangements, etc), the development of novel algorithms for specific research questions, data interpretation (prioritization of identified genetic variants through data fusion, advanced pathway analyses and the application of advanced modeling approaches to predict disease-relevant characteristics). Additionally, each of these projects also involves the functional validation of the genetic/bio-informatic findings in models organisms using standard molecular biology and functional genomic tools.
Profile:
• You hold a PhD in biological of medical sciences but are familiar with computer science, bioinformatics or applied statistics and ideally also have initial experience with applications on high-dimensional data (Microarray or Next-Generation Sequencing). You are interested in a research staff position or a post-doctoral position;
• Alternatively, you may also have a master’s degree in industrial engineering or a master’s degree in civil or bio-engineering with expertise in computer science;
• You have organizational and management skills, and you can inspire and motivate the team for your work;
• You have good communication skills and can cooperate easily with the different team members;
• You have passion for science and the motivation to work on an innovative and ambitious project in an open, dynamic and skilled team;
• You have experience with programming languages (such as Perl, Matlab or R).
• Your preferred skills are:
• Knowledge of Linux, R, Perl and Bash scripting;
• Experience with next-generation sequencing data analyses;
• Basic system administration skills are considered a plus.
Contact:
To find out more about the project, the scientific challenge and the training opportunities, contact Diether Lambrechts who is heading the Laboratory of Translational Genetics (address department).
We offer:
We offer a dynamic working environment at the VIB-VRC located in Leuven, a competitive remuneration package, the opportunity to contribute to ambitious research projects from a young and motivated team and the possibility to be at the start of a scientifically cutting-edge and socially relevant project.
To meet the increasing demands of performing multidisciplinary research, VRC offers Core facilities including Imaging, Molecular Biology, Proteomics, Histology, Aquatic facility (zebrafish & tadpoles), Mouse facility, etc. Specifically, for the current position, access to next-generation sequencing is enabled through the Genomics Core Facility (HiSEQ2000, Illumina iSCAN are operational) and the IT Infrastructure Unit (high-capacity computing clusters and data storage).
Qualified senior candidates will have the possibility to mentor junior scientists and technicians, and work semi-independently.
Starting date: as soon as possible
Applications:
Please send a complete CV, a list of publications, a summary of past research and the contact information of 2 or 3 referees. Top-ranked candidates will be invited for an interview in Leuven.
Applications should be submitted to evelien.verdrengh at vib-kuleuven.be
Position:
In the Laboratory of Translational Genetics located in Leuven, we are offering a research position in bio-informatics to assist with the analysis of next-generation sequencing data. Ideally, the holder of the position will be scientifically coordinating one or two research projects as a leading scientist and for this, will be able to rely on available data analysis pipelines and IT infrastructure. Additionally, he/she should be willing to participate in a number of collaborative projects within the Laboratory of Translational Genetics by performing advanced bio-informatics consulting and data analysis.
Who should apply for this job?
“If you are fascinated by computer science and have an extra-ordinary curiosity in biology and medicine, if you are driven by a wish to make a difference, if you enjoy and foster team work, if you consider yourself a “bridge” in your social network, if you are not phased by the unknown, willing to push the limits and ready to tackle a challenge, then this job could be just right for you.
Context:
Research in the Laboratory for Translational Genetics aims to unravel the genetic predisposition to cancer and annotate somatic changes in solid tumors with the ultimate aim to discover and functionally validate genetic biomarkers for cancer therapies. To this extend, state-of-the-art high throughput technologies are being used, including large-scale next-generation sequencing of DNA and RNA samples. One of the most exciting ongoing projects concerns the analysis of whole-genome sequencing data of tumor samples. Additionally, a number of projects involve the analysis of ChiPSeq data to characterize epigenetic modifications of (tumor) genomes and based on these data identify novel transcriptional regulatory networks. A key aspect in each of these projects is the use of specialized bio-informatics for primary data analyses (sequence assembly, mapping of deletions, amplifications, tandem duplications, invertions and interchromosomal rearrangements, etc), the development of novel algorithms for specific research questions, data interpretation (prioritization of identified genetic variants through data fusion, advanced pathway analyses and the application of advanced modeling approaches to predict disease-relevant characteristics). Additionally, each of these projects also involves the functional validation of the genetic/bio-informatic findings in models organisms using standard molecular biology and functional genomic tools.
Profile:
• You hold a PhD in biological of medical sciences but are familiar with computer science, bioinformatics or applied statistics and ideally also have initial experience with applications on high-dimensional data (Microarray or Next-Generation Sequencing). You are interested in a research staff position or a post-doctoral position;
• Alternatively, you may also have a master’s degree in industrial engineering or a master’s degree in civil or bio-engineering with expertise in computer science;
• You have organizational and management skills, and you can inspire and motivate the team for your work;
• You have good communication skills and can cooperate easily with the different team members;
• You have passion for science and the motivation to work on an innovative and ambitious project in an open, dynamic and skilled team;
• You have experience with programming languages (such as Perl, Matlab or R).
• Your preferred skills are:
• Knowledge of Linux, R, Perl and Bash scripting;
• Experience with next-generation sequencing data analyses;
• Basic system administration skills are considered a plus.
Contact:
To find out more about the project, the scientific challenge and the training opportunities, contact Diether Lambrechts who is heading the Laboratory of Translational Genetics (address department).
We offer:
We offer a dynamic working environment at the VIB-VRC located in Leuven, a competitive remuneration package, the opportunity to contribute to ambitious research projects from a young and motivated team and the possibility to be at the start of a scientifically cutting-edge and socially relevant project.
To meet the increasing demands of performing multidisciplinary research, VRC offers Core facilities including Imaging, Molecular Biology, Proteomics, Histology, Aquatic facility (zebrafish & tadpoles), Mouse facility, etc. Specifically, for the current position, access to next-generation sequencing is enabled through the Genomics Core Facility (HiSEQ2000, Illumina iSCAN are operational) and the IT Infrastructure Unit (high-capacity computing clusters and data storage).
Qualified senior candidates will have the possibility to mentor junior scientists and technicians, and work semi-independently.
Starting date: as soon as possible
Applications:
Please send a complete CV, a list of publications, a summary of past research and the contact information of 2 or 3 referees. Top-ranked candidates will be invited for an interview in Leuven.
Applications should be submitted to evelien.verdrengh at vib-kuleuven.be