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Old 02-04-2011, 05:08 PM   #1
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Location: Redwood City

Join Date: Sep 2010
Posts: 4
Default Senior Bioinformatics Developer/ Contractor


We are looking for an experienced biomedical informatics developer to join a dynamic project team developing the next generation of drug target identification and development tools for biomedical researchers.


Essential Functions:
Develop software for integration of heterogeous biological data types using semantic web as well as traditional bioinformatics techniques
Implement hypothesis identification, comparison, and scoring analytics for knowledge-based computational systems biology system that enables biomedical researchers to make effective drug target selection decisions
Performance tuning and optimization of algorithms and bioinformatics data processing pipelines
Participate in the design and implementation of data sources used by analytics

Marginal Functions:
Extend and integrate computable disease models used by analytics


Strong applied math skills in graph theory and statistics, ability to reason using summary statistics
Understanding of target identification approaches for drug discovery
Demonstrated ability to develop innovative ideas and execute effectively against them in a highly collaborative environment
Familiarity with biomedical ontologies (e.g. GO, UMLS), biomedical data exchange formats (e.g. SBML, BioPax), and biomedical databases (e.g. MEDLINE)
Working understanding of molecular and cellular biology concepts, and eagerness to help advance biomedical discovery
Knowledge of scientific computing workflows, including analytics, visualization and pipeline workflow for data processing
Ability to work effectively in an agile, release-early release-often development environment
Ability to select among existing methodologies and tools, and where necessary develop new approaches, to drive design processes and communicate design rationales
Exceptional analytic thinking and demonstrated ability to independently analyze large-scale datasets
Expert Excel skills and ability to use basic statistical packages (e.g. R)
Strong visual, verbal, and written communication skills


Experience using biomedical ontologies (MeSH, UMLS, GO, etc), controlled vocabularies, or semantic datasets (RDFS, OWL, etc)
Experience developing scientific analytics or pipelines used in drug discovery workflows

Experience developing in an agile team-based environment, including knowledge of SVN, continuous integration, etc.
Experience developing web-based front-ends for scientific computing resources, with an understanding of modern web frameworks
3+ years experience programming Java


5+ years bioinformatics experience with a MS or higher degree in Computer Science, Bioinformatics, or related field
7+ years industry experience with a PhD in Biomedical Informatics

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