I just made an amazing discovery : the content of CG-binucleotides
in human DNA is much lower (~one fourth) of the content of other
binucleotides, e.g. GC.
This is so basic, fundamental, that it must be known and there should
be a keyword where/how to find more about it ?!
But I never saw it.
The ratio (number of GC)/number of CG) seems to depend on
chromosome-length, it's also seen in other vertibrates,
average ratio maybe 2 ,
not in invertibrates,viruses, bacteria where I got a ratio of ~1.2,
except HIV with 5.8(!) , influenza with 2.2
hepatitis with 1.35 , oryza 1.39 , gallus 5.0 , influenza-B 2.8
human mitochondrial DNA 1.63
human chr01:4.36
human chr22:3.44
so, how is this phenomenon called ? Where to find more about it ?
is it because the assembling of CG takes longer and is thus avoided ?
human chromosome 1:
AA,21387422
AC,11301414
AG,16036982
AT,16766098
CA,16363109
CC,12259077
CG, 2281713
CT,16060830
GA,13448131
GC, 9938922
GG,12248730
GT,11320734
TA,14293281
TC,13465343
TG,16389034
TT,21438891
GC/CG-ratio=4.355904
--------------------------------------------------
OK, I found the answer now myself : "DNA-methylation"
----------------------------------------------------
in human DNA is much lower (~one fourth) of the content of other
binucleotides, e.g. GC.
This is so basic, fundamental, that it must be known and there should
be a keyword where/how to find more about it ?!
But I never saw it.
The ratio (number of GC)/number of CG) seems to depend on
chromosome-length, it's also seen in other vertibrates,
average ratio maybe 2 ,
not in invertibrates,viruses, bacteria where I got a ratio of ~1.2,
except HIV with 5.8(!) , influenza with 2.2
hepatitis with 1.35 , oryza 1.39 , gallus 5.0 , influenza-B 2.8
human mitochondrial DNA 1.63
human chr01:4.36
human chr22:3.44
so, how is this phenomenon called ? Where to find more about it ?
is it because the assembling of CG takes longer and is thus avoided ?
human chromosome 1:
AA,21387422
AC,11301414
AG,16036982
AT,16766098
CA,16363109
CC,12259077
CG, 2281713
CT,16060830
GA,13448131
GC, 9938922
GG,12248730
GT,11320734
TA,14293281
TC,13465343
TG,16389034
TT,21438891
GC/CG-ratio=4.355904
--------------------------------------------------
OK, I found the answer now myself : "DNA-methylation"
----------------------------------------------------
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