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Old 02-01-2016, 02:11 PM   #1
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Default Assembling Another Genome based on a Reference

I have a bacteria sample, and I have done genome assembly and now have its original sequence. Since the bacteria sample has come from the soil, it contained two closely related bacterias. How can I use the reference genome that I now have to assemble the "other" genome? Which programs can be helpful?
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Old 02-01-2016, 03:21 PM   #2
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I think assemblers like mira and velvet give you the option of using a reference.
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Old 02-02-2016, 11:45 PM   #3
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Try also a more recent effort, Medusa
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assembly, velvet

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