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  • Establishing a metagenomics lab/hardware requirements

    Hello all!

    I recently joined a lab that would like to set up a bioinformatics side of things. We do a lot of stool sample shotgun sequencing and we get loads of samples (in the thousands) sequenced to medium - deep sequencing (~10million reads per sample). At the moment we are still at the sequencing stage, so no analysis has started yet of the sequencing results.

    For that we need to greatly upgrade our hardware. If one were to buy a workstation (instead of regular desktop or perhaps a server) what kind of specs would you suggest this workstation to have?

    I am thinking the three things that are super important in decreasing order is RAM, space, and processing power.

    For RAM, would you say for the amount of samples i referred to above, would below 100Gb be sufficient or should we be aiming for more?

    For space, would you say tens of terabytes would be sufficient or should we aim already for hundreds of terabytes.

    Finally, what kind of CPUs would you recommend? Would the intel ones be good enough i7 or i9? Is something else more state of the art this kind of analysis?

    I have tried to do as much research as i can on my own but i am no bioinformatician! Any input would help

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