new BGI sequencer can sequence 1mil genomes/year

ymc · 01-22-2015, 12:32 AM

BGI will release two sequencers this year. One big one small. The big one can sequence 1 million genomes per year. No details on the small one. Exact spec will be announced in Q2:

http://seq.cn/portal.php?mod=view&aid=15782

Well, HiSeq X Ten can only do 2400 genomes per machine per year. Assuming this big sequencer is also selling in ten packs, then its throughput is 40x of HiSeq X. Too good to be true???

hellsingwyk · 01-22-2015, 12:40 AM

In fact, "BGI sequencer" are developed by Complete Genomics........

GenoMax · 01-22-2015, 04:02 AM

It is always good to have additional options .. specially if the pricing is reasonable.

That said providing field support (applications/software) for new instruments is not trivial but perhaps BGI has the money do that as well.

sklages · 01-22-2015, 04:37 AM

Quote:

Originally Posted by ymc

http://seq.cn/portal.php?mod=view&aid=15782

Not too many words I understood .. couldn't find the "switch to english language" button ;-)

GenoMax · 01-22-2015, 04:43 AM

http://translate.google.com

Paste the URL in.

You can translate to German also :-)

sklages · 01-22-2015, 05:13 AM

ha, good hint .. never used it to translate a whole website. :-)

ymc · 01-22-2015, 10:33 AM

ah.. I think I understand now. BGI used to quote one genome as 1x genome not 30x genome. So they are in fact claiming they can make a machine at a throughput similar to HiSeq X.

How's the error rate of Complete Genomics? How does it compare to Illumina machines?

Geneus · 01-22-2015, 10:35 AM

1,000,000 genomes per year? Kind of like the claim BGI had a few years ago about having 1000 bioinformaticians.

Maybe someone got their powers of 10 off a couple of places.

Chipper · 01-22-2015, 11:16 AM

The linked text is just a translation of the Genomeweb article I would guess. In there they discuss BGI:s "Million genomes" project, not 1 million genomes per year.

If I remember correctly, CG now uses an ordered flow cell with 6 billion clusters, one cluster per pixel. Aiming for cameras capable of 500 MP/s (?), not sure what that would translate to in terms of genomes / year. 100 bp reads with long fragment technology and higher quality than Illumina.

chengang · 03-02-2015, 09:43 AM

BGI will launch at least two new sequencers this year. We will start some early-access projects to benchmark the new sequencers soon.

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01-22-2015, 12:32 AM	#1
ymc Senior Member Location: Hong Kong Join Date: Mar 2010 Posts: 498	new BGI sequencer can sequence 1mil genomes/year BGI will release two sequencers this year. One big one small. The big one can sequence 1 million genomes per year. No details on the small one. Exact spec will be announced in Q2: http://seq.cn/portal.php?mod=view&aid=15782 Well, HiSeq X Ten can only do 2400 genomes per machine per year. Assuming this big sequencer is also selling in ten packs, then its throughput is 40x of HiSeq X. Too good to be true???

01-22-2015, 12:40 AM	#2
hellsingwyk Member Location: HK Join Date: Sep 2012 Posts: 18	In fact, "BGI sequencer" are developed by Complete Genomics........

01-22-2015, 04:02 AM	#3
GenoMax Senior Member Location: East Coast USA Join Date: Feb 2008 Posts: 7,091	It is always good to have additional options .. specially if the pricing is reasonable. That said providing field support (applications/software) for new instruments is not trivial but perhaps BGI has the money do that as well.

01-22-2015, 04:43 AM	#5
GenoMax Senior Member Location: East Coast USA Join Date: Feb 2008 Posts: 7,091	http://translate.google.com Paste the URL in. You can translate to German also :-)

01-22-2015, 05:13 AM	#6
sklages Senior Member Location: Berlin, DE Join Date: May 2008 Posts: 628	ha, good hint .. never used it to translate a whole website. :-)

01-22-2015, 10:33 AM	#7
ymc Senior Member Location: Hong Kong Join Date: Mar 2010 Posts: 498	ah.. I think I understand now. BGI used to quote one genome as 1x genome not 30x genome. So they are in fact claiming they can make a machine at a throughput similar to HiSeq X. How's the error rate of Complete Genomics? How does it compare to Illumina machines?

01-22-2015, 10:35 AM	#8
Geneus Member Location: New Jersey Join Date: Dec 2010 Posts: 61	1,000,000 genomes per year? Kind of like the claim BGI had a few years ago about having 1000 bioinformaticians. Maybe someone got their powers of 10 off a couple of places.

01-22-2015, 11:16 AM	#9
Chipper Senior Member Location: Sweden Join Date: Mar 2008 Posts: 324	The linked text is just a translation of the Genomeweb article I would guess. In there they discuss BGI:s "Million genomes" project, not 1 million genomes per year. If I remember correctly, CG now uses an ordered flow cell with 6 billion clusters, one cluster per pixel. Aiming for cameras capable of 500 MP/s (?), not sure what that would translate to in terms of genomes / year. 100 bp reads with long fragment technology and higher quality than Illumina.

03-02-2015, 09:43 AM	#10
chengang Junior Member Location: China Join Date: Feb 2014 Posts: 2	BGI will launch at least two new sequencers this year. We will start some early-access projects to benchmark the new sequencers soon.