Hi,
I'm fairly new to chip seq and I've been given some transcription factor datasets to rummage through. I found some lovely peaks (consistent in 4 different samples) just beyond the 3' end of a really interesting candidate gene (actively transcribed). Are there any examples where TF binding beyond the 3' end of a gene has been shown as functional? Like a 'backward' promoter if you will?
Any suggestions appreciated, apologies if it's a daft question!
Livi
ps. the nearest gene other than my interesting candidate is over 30kb downstream
I'm fairly new to chip seq and I've been given some transcription factor datasets to rummage through. I found some lovely peaks (consistent in 4 different samples) just beyond the 3' end of a really interesting candidate gene (actively transcribed). Are there any examples where TF binding beyond the 3' end of a gene has been shown as functional? Like a 'backward' promoter if you will?
Any suggestions appreciated, apologies if it's a daft question!
Livi
ps. the nearest gene other than my interesting candidate is over 30kb downstream
Comment