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Old 12-06-2012, 10:31 PM   #1
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Location: San Francisco

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Default Simple question: Who actually discovered 5 methyl C?

For some reason this information is not readily available. Just want to know who to give the nobel prize to.
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Old 05-19-2014, 05:46 AM   #2
Location: Münster, Germany

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As usual, there is not a simple answer.

Frequently Rollin Hotchkiss is credited, because he was the first to describe "Epi-cytosine" as a distinct, but chemically very similar base to cytosine. (see Fig. 2)

However he established no link to epigenetics and also did not investigate the exact chemical structure of "Epi-Cytosine". The identification as 5mC was achieved by Waldo Cohn in 1951 .
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