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Old 04-19-2016, 10:36 PM   #1
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Location: Los Angeles

Join Date: Feb 2015
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Default Fragment Analyzer-Advanced Analytical

Hi, does anyone know how the Fragment Analyzer from Advanced Analytical perform compared to the Agilent Bioanalyzer and Tapestation? I am interested in the quality, reliability, and cost comparison. I saw some threads in the past on this subject, but wonder if anyone has any updated info on this instrument?

Thanks so much!
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Old 04-20-2016, 03:51 AM   #2
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Location: France

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Fragment analyzer is a very powerfull machine. We use it routinely because our is a 96 capillary system, and we can put 3 or 4 plates in a same time.
We have also bioanalyzer to perform DNA 1000 or HS chip but it is only for 12 or 11 samples.
Fragment analyzer is cheaper than bioanalyzer if you have plenty of samples
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Old 04-20-2016, 05:58 AM   #3
Location: Illinois

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We did a head to head comparison of the Fragment analyzer and the Bioanalyzer for RNA QC. In terms of sensitivity, the Bioanalyzer was more sensitive in detecting low input total RNA (50-100 pg/uL). Cost/sample is lower for the Fragment analyzer and it certainly has a lot of things going for it if you are just using final QC of NGS libs. Depending on which capillary head you get on it (12,48, or 96), you can get a couple of Bioanalyzers for the same cost. I recommend you demo it to see how it fits your needs. Really depends on your throughput needs.
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