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With the HiSeq platforms (2500 and X), Illumina is dominating genome sequencing (WGS and exome). But for RNA-Seq, does the Proton have a chance? We lay out the case in our latest blog.
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A single-molecule sequencer with an oligo-dT flowcell? -
Well, the Heliscope never sold well, but Helicos didn't really focus on counting applications in the beginning. Perhaps if they had that platform would have found a niche that allowed it to survive. (But you can still use it as a service via SeqLL.com)Originally posted by Chipper View PostComment
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The field of epigenetics has traditionally concentrated more on DNA and how changes like methylation and phosphorylation of histones impact gene expression and regulation. However, our increased understanding of RNA modifications and their importance in cellular processes has led to a rise in epitranscriptomics research. “Epitranscriptomics brings together the concepts of epigenetics and gene expression,” explained Adrien Leger, PhD, Principal Research Scientist...Yesterday, 07:01 AM -
Proteins are often described as the workhorses of the cell, and identifying their sequences is key to understanding their role in biological processes and disease. Currently, the most common technique used to determine protein sequences is mass spectrometry. While still a valuable tool, mass spectrometry faces several limitations and requires a highly experienced scientist familiar with the equipment to operate it. Additionally, other proteomic methods, like affinity assays, are constrained...04-04-2024, 04:25 PM
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