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We recently purchased an S5 and are planning to bring a test onboard that was done on a proton. The proton using a P1 would consistently give over 90 million total reads. However, on the S5 that same sample using a 540 yields 80 million reads consistently. Is the chemistry different in the proton compared to the S5 or something else? I thought the 540 was comparable to the P1? Is there a way to achieve 90 million reads on the S5? Thanks.
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The sequencing world is rapidly changing due to declining costs, enhanced accuracies, and the advent of newer, cutting-edge instruments. Equally important to these developments are improvements in sequencing analysis, a process that converts vast amounts of raw data into a comprehensible and meaningful form. This complex task requires expertise and the right analysis tools. In this article, we highlight the progress and innovation in sequencing analysis by reviewing several of the...Today, 07:48 AM -
The field of epigenetics has traditionally concentrated more on DNA and how changes like methylation and phosphorylation of histones impact gene expression and regulation. However, our increased understanding of RNA modifications and their importance in cellular processes has led to a rise in epitranscriptomics research. “Epitranscriptomics brings together the concepts of epigenetics and gene expression,” explained Adrien Leger, PhD, Principal Research Scientist...04-22-2024, 07:01 AM
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