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  • Fragment Library vs Mate-pair library

    The SOLid system allows the research 2 choices for sample preparation, the fragment library or mate-pair library in which fragment library involve single fragment DNA while mate-pair library involve two fragments of DNA.

    Why is that need this two different sample preparation method?

    What kind of situation we use these different method?

  • #2
    mate-pair : structural variation, regions of large repeats or mutations, indels, unique coverage, complex genome snp discovery

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