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Old 07-14-2010, 04:05 PM   #1
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Default Sensitivity of Mutant Detection


I really wish to find out what is the best platform (Illumina GAII, Roche 454, ABI SOLiD, or 3rd generation such as PacBio and Hellicos) for high sensitivity mutation detection, i.e. a platform able to detect and quantify low frequency, e.g. <1%, of somatic mutations in the major oncogenes and tumor suppressor genes after target capture.

Any feedback is highly appreciated!

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