CSHL, UCLA & Einstein to Lead Roundtable Discussions on Single-Cell Sequencing

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Open to all attendees, speakers, sponsors, & exhibitors of Single-Cell Sequencing at Next Generation Dx Summit are three roundtable discussions on the following key issues:

Making Single-Cell Analysis Cost Effective for Clinical Use
Moderator: James Hicks, Ph.D., Research Professor, Cancer Genomics, Cold Spring Harbor Laboratory

• Methods for capture: What are the tradeoffs?
• Combining RNA, DNA and protein analysis
• What genomic assays are most informative?
• Can assays be certifiable?

Finding a Needle in a Haystack: Towards Diagnosing Rare Soft Tissue Cancer Stem Cells (CSCs)
Moderator: Michael Masterman-Smith, Ph.D., Entrepreneurial Scientist, UCLA California NanoSystems Institute

• Rethinking companion diagnostics for cancer to incorporate analysis of CSCs
• Current direct methodologies of CSC detection/isolatio
• Current proxy methodologies of CSC detection/isolation
• The hope and promise of single-cell assay tools and technologies

Why Single-Cell Sequencing?
Moderator: Jan Vijg, Ph.D., Professor and Chairman, Genetics, Albert Einstein College of Medicine

• Sample limitations, e.g., prenatal diagnostics and CTCs
• To study cell-to-cell variation, e.g., in tumors as well as normal tissues
• To overcome technological constraints, e.g., detecting somatic mutations
• Cell-to-cell fluctuations in gene expression can easily impair function, yet can be undetectable by measuring averages
• How many different cell types are there?

The discussions will be held on the second day of the Single-Cell Sequencing Conference at Next Generation Dx Summit, taking place August 20-21, 2014 in Washington, DC. For full program details and to register, please visit http://www.nextgenerationdx.com/Single-Cell-Sequencing