Seqanswers Leaderboard Ad

Collapse

Announcement

Collapse
No announcement yet.
X
 
  • Filter
  • Time
  • Show
Clear All
new posts

  • Coordinating sequencing data and microarrays

    I'm sure this is a very simple question, but I am still getting a feel for how locations are named.

    Let's assume that I've processed an individual's genome (possibly from 1000 genomes) and I identified a consensus sequence for that individual.

    I want to compare the sequencing calls to microarray calls for those SNPs on an array. How do I identify the positions in the sequencing that are located on the array?

  • #2
    Originally posted by bio View Post
    I'm sure this is a very simple question, but I am still getting a feel for how locations are named.

    Let's assume that I've processed an individual's genome (possibly from 1000 genomes) and I identified a consensus sequence for that individual.

    I want to compare the sequencing calls to microarray calls for those SNPs on an array. How do I identify the positions in the sequencing that are located on the array?
    This seems like an extremely basic bioinformatics question. I would ask your local bioinformatician or your PI for help getting accustomed to such data.

    Comment


    • #3
      1000 Genomes microarray data

      In the specific instance of 1000 Genomes data, does anyone know if the microarray calls or (preferably) raw array data are available for download? These were used to validate NSG-based SNP calls as mentioned in the pilot paper. Further, for full project data (e.g. high coverage full exome), will this data be made available as it is generated? Is some of it already available?

      I haven't seen this data at the project FTP site.

      Comment

      Latest Articles

      Collapse

      • seqadmin
        Current Approaches to Protein Sequencing
        by seqadmin


        Proteins are often described as the workhorses of the cell, and identifying their sequences is key to understanding their role in biological processes and disease. Currently, the most common technique used to determine protein sequences is mass spectrometry. While still a valuable tool, mass spectrometry faces several limitations and requires a highly experienced scientist familiar with the equipment to operate it. Additionally, other proteomic methods, like affinity assays, are constrained...
        04-04-2024, 04:25 PM
      • seqadmin
        Strategies for Sequencing Challenging Samples
        by seqadmin


        Despite advancements in sequencing platforms and related sample preparation technologies, certain sample types continue to present significant challenges that can compromise sequencing results. Pedro Echave, Senior Manager of the Global Business Segment at Revvity, explained that the success of a sequencing experiment ultimately depends on the amount and integrity of the nucleic acid template (RNA or DNA) obtained from a sample. “The better the quality of the nucleic acid isolated...
        03-22-2024, 06:39 AM

      ad_right_rmr

      Collapse

      News

      Collapse

      Topics Statistics Last Post
      Started by seqadmin, 04-11-2024, 12:08 PM
      0 responses
      17 views
      0 likes
      Last Post seqadmin  
      Started by seqadmin, 04-10-2024, 10:19 PM
      0 responses
      22 views
      0 likes
      Last Post seqadmin  
      Started by seqadmin, 04-10-2024, 09:21 AM
      0 responses
      16 views
      0 likes
      Last Post seqadmin  
      Started by seqadmin, 04-04-2024, 09:00 AM
      0 responses
      46 views
      0 likes
      Last Post seqadmin  
      Working...
      X